alpha-Synuclein PFF mouse cortex GeoMxSegments were captured from specific cortical layers of wildtype mice injected with α-synuclein PFFs in the dorsal striatum, capturing whole transcriptomes from neurons positive for α-synuclein inclusions, or negative for α-synuclein inclusions using the GeoMx WTA platform. ASAP Team: Biederer Dataset Name: biederer-mouse-spatial-geomx-lamda, v1.0 Principal Investigator: Thomas Biederer Co-Principal Investigator: Michael Henderson Contributors: Goralski, Thomas; Meyerdirk, Lindsay; Breton, Libby; Brasseur, Laura; Kurgat, Kevin; DeWeerd, Daniella; Turner, Lisa; Becker, Katelyn; Adams, Marie; Newhouse, Daniel; Henderson, Michael Sample Summary: Resources and Additional Information Protocols GitHub: https://github.com/Goralsth/Spatial-transcriptomics-reveals-molecular-dysfunction-associated-with-cortical-Lewy-pathology Protocols: https://doi.org/10.17504/protocols.io.bp2l6xwmklqe/v1; https://doi.org/10.17504/protocols.io.yxmvm3zy5l3p/v1; https://doi.org/10.17504/protocols.io.dm6gpbrw1lzp/v1; https://doi.org/10.17504/protocols.io.5jyl89m9dv2w/v1; https://doi.org/10.17504/protocols.io.bp2l61n91vqe/v1; https://doi.org/10.17504/protocols.io.4r3l22y6jl1y/v1 Dataset DOI:...Access requires approval by the data custodian. The collection's description and structure are public; querying the data requires an approved request.alpha-Synuclein PFF mouse cortex GeoMx is published on ASAP CRN Cloud.